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HALO® is a series of (U)HPLC columns based on the core-shell (FusedCore™) technology. The manufacturer of these columns is Advanced Materials Technology™ (AMT), whose founders was outstanding pioneers from the field of high-performance liquid chromatography. AMT is the genuine developer and producer of of packing materials with FusedCore™ technology. The silica-based stationary phases consist of a non-porous core and an porous outer layer, that provides fast separations without excessive backpressure. HALO® columns are available in different particle sizes: 2 μm (core: 1.2 μm), 2.7 μm (core: 1.7 μm), 3.4 μm (only HALO® Protein columns, core: 3.0 μm) and 4.6 μm (core: 3.3 μm) and with various modifications that cover a wide selectivity range. HALO® Bioclass columns have been specially designed for the separation of biomolecules such as proteins, peptides or glycans. HALO® Enviroclass columns are designed for environmental analysis.