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Vial Inserts
Vial inserts are an essential component in chromatography and play an important role in sample preparation and analysis. These small inserts, which are inserted into the vials, offer numerous advantages, especially when it comes to handling small sample volumes and avoiding sample loss.
Vial inserts are available in various shapes, sizes and materials to meet the different requirements of chromatography. The most common materials are glass and plastic. Glass inserts are chemically inert and are particularly suitable for samples that are sensitive to chemical interactions. Plastic inserts, usually made of polypropylene, are resistant to many solvents and offer a cost-effective alternative to glass inserts.
A major advantage of vial inserts is the reduction in dead volume. In chromatography, even a small amount of lost sample can influence the accuracy of the results. By using inserts, the dead volume is minimised, which is particularly important when analysing small sample quantities. This enables a more precise and reproducible analysis.
There are different types of vial inserts, including conical and flat inserts. Conical inserts are particularly advantageous when it comes to reaching the entire sample volume with the needle of the autosampler, as the conical shape concentrates the sample in a small area. Flat inserts, on the other hand, offer a larger surface area, which can be an advantage in certain applications.
Another important aspect is the compatibility of the inserts with the vials and the autosamplers used. It is crucial that the inserts sit firmly in the vials and do not slip during the analysis. Some inserts are also provided with filling lines that facilitate the precise filling of the samples and improve reproducibility.
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