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BioResolve

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BioResolve

BioResolve columns from Waters are HPLC and UHPLC columns for the analysis of biomolecules and in particular mAb-based and related biotherapeutics. Three different modifications are available for different applications:

BioResolve RP mAb Polyphenyl: Polyphenyl modification for reversed-phase chromatography; material based on fused-core technology; for the analysis of intact and IdeS-digested mAbs
BioResolve SCX mAb: cation exchange modification; material is non-porous polymer according to L34; for the analysis of antibody charge variants
BioResolve SEC mAb : size exclusion modification; fully porous hybrid material; for the analysis of mAb aggregates (HMWS), monomers and fragments (LMWS)

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BioResolve SEC mAb Guard, 200Å, 2.5 µm, 4.6 x 30 mm, 1/pk;

186009443

€510.00

Product Type: SEC/GPC Guard Columns Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Endcapping: non endcapped Manufacturer: Waters Matrix: Hybrid Internal Diameter: 4.6 mm Length: 30 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: HPLC USP Class: L33

BioResolve SEC mAb Column, 200Å, 2.5 µm, 7.8 x 300 mm, 1/pk;

186009441

€3,610.00

Product Type: SEC/GPC Columns Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 7.8 mm Length: 300 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Column, 200Å, 2.5 µm, 7.8 x 150 mm, 1/pk;

186009439

€2,480.00

Product Type: SEC/GPC Columns Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 7.8 mm Length: 150 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Column, 200Å, 2.5 µm, 4.6 x 300 mm, 1/pk;

186009437

€3,430.00

Product Type: SEC/GPC Columns Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 4.6 mm Length: 300 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Column, 200Å, 2.5 µm, 4.6 x 150 mm, 1/pk;

186009435

€2,300.00

Product Type: SEC/GPC Columns Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 4.6 mm Length: 150 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve Phenyl Guard Column, 450Å, 2.7 µm, 2.1 mm X 30 mm, 1/pk;

186009270

€765.00

Product Type: HPLC Guard Columns Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Endcapping: endcapped Manufacturer: Waters Matrix: Silica Internal Diameter: 2.1 mm Length: 30 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 450 Å Temperature Maximum [°C]: 90

BioResolve SCX mAb Method Validation Kit, 3 µm, 4.6 mm x 100 mm, 3/pk;

186009200

€4,470.00

Product Type: HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Strong cation-exchange Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Polymer Internal Diameter: 4.6 mm Length: 100 mm Particle Morphology: spherical, non-porous pH Minimum: 3.0 pH Maximum: 11.0 Pressure Stability: 689 bar Technology: HPLC

BioResolve SCX mAb Method Validation Kit with VanGuard FIT, 3 µm, 4.6 mm x 100 mm, 3/pk;

186009199

€5,330.00

BioResolve SCX mAb Method Validation Kit, 3 µm, 2.1 mm x 100 mm, 3/pk;

186009198

€4,100.00

Product Type: HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Strong cation-exchange Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Polymer Internal Diameter: 2.1 mm Length: 100 mm Particle Morphology: spherical, non-porous pH Minimum: 3.0 pH Maximum: 11.0 Pressure Stability: 689 bar Technology: HPLC

BioResolve SCX mAb Method Validation Kit with VanGuard FIT, 3 µm, 2.1 mm x 100 mm, 3/pk;

186009197

€4,950.00

Product Type: HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Strong cation-exchange Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Polymer Internal Diameter: 2.1 mm Length: 100 mm Particle Morphology: spherical, non-porous pH Minimum: 3.0 pH Maximum: 11.0 Pressure Stability: 689 bar Technology: HPLC

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Technical Data

Phase	Modification	Particle size	Pore size	Surface area	C-content	Endcapped	USP	pH range
BioResolve mAb Polyphenyl	Phenyl	2.7 µm	450 Å	N/A	N/A	+	L11	1.0-8.0
BioResolve SCX mAb	N/A	3 µm	non-porous	N/A	N/A	+	L34	2.0-7.0
BioResolve SEC mAb	Diol	2.5 µm	200 Å	220 m²/g	12 %C	-	L20, L33, L59	2.5-8.0

Downloads

Brochures

HPLC SEC Sample Preparation
Waters Catalog 23-24 Biomolecule HPLC SEC SPE Brochure
SEC Standards
Waters Catalog 23-24 SEC Columns Standards SEC Brochure

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