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Toyopearl resins, manufactured by Tosoh Bioscience, are hydrophilic macroporous methacrylic resins for large-scale chromatographic applications. A comprehensive range of media for all common modes of liquid chromatography, including ion-exchange, hydrophobic interaction, reversed-phase, size exclusion and affinity, are available. They exhibit high mechanical and chemical stability and are stable from pH 2 – 12 for normal operating conditions and pH 1 – 13 for cleaning conditions. The resins are available in average particle sizes of 35 μm, 45 µm, 65 μm, 75 μm, and 100 μm for high resolution, intermediate purification, or capture chromatography.
For predictable results in scale-up, Toyopearl resins are based on the same chemistries as the analytical TSKgel PW columns. This allows the seamless direct scale-up of methods developed on TSKgel columns to Toyopearl resins.
Toyopearl Resins are available as bulk material in various packaging sizes. In addition, for most Toyopearl resins, pre-packed Minichrom® columns are available. The most popular TOYOPEARL resins are also available in RoboColumn® format.
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