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HyPURITYâ„¢ HPLC Columns manufactured by Thermo Scientificâ„¢ are highly characterized, tested and validated columns with exceptional reproducibility. The base material is a ultra pure, stable silica, which enhances column lifetime, performance and reliability. The columns show superior efficiency and peak shape for a wide range of analytes. HyPURITY ADVANCEâ„¢ is a polar-embedded phase. HyPURITY AQUASTARâ„¢ is a polar endcapped phase with alternative selectivity. Both phases are compatible with highly polar eluents.