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ChiroSil
ChiroSil® columns are based on materials modified with chiral crown ethers. A covalent bond to silica ensures excellent column stability. The main area of application is the enantiomer separation of primary amines, amino acids and corresponding derivatives. The columns are available with both enantiomeric forms RCA (+) and SCA (-), allowing the elution sequence to be inverted. In addition, ChirolSil® columns can be used in normal and reversed phase chromatography respectively. All ChirolSil® columns are also available in the ChirolSil ME® version with higher capacity factors.
Technical Data
| Phase | Modification | Particle size | Pore size |
| ChiroSil RCA (+) | (+)-(18-crown-6)-tetracarboxylic acid | 5 µm, 10 µm | 100 Å |
| ChiroSil SCA (-) | (-)-(18-crown-6)-tetracarboxylic acid | 5 µm, 10 µm | 100 Å |
| ChiroSil ME RCA (+) | (+)-(18-crown-6)-tetracarboxylic acid | 5 µm, 10 µm | 100 Å |
| ChiroSil ME SCA (-) | (-)-(18-crown-6)-tetracarboxylic acid | 5 µm, 10 µm | 100 Å |
Downloads
Brochures
Regis Technologies Chromatography Catalog
Regis Technologies Chiral Stationary Phases Catalogue
Applications
Regis Technologies Chiral Handbook - HPLC and SFC Separations
Regis Technologies Chirosil Improved Chiral Separations for Enantiopure D- & L-Amino Acids
Technical Support
Regis Technologies ChiroSil Care and Use Guide
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