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Supelcosil™ is a family of HPLC columns, manufactured by Supelco™ (Sigma-Aldrich™). The Phases based on spherical type-A silica, which is available in many different modifications for various separation techniques, e.g. Reversed-Phase‒, Normal-Phase‒ or Ion-Exchange-Chromatography.
Supelcosil™ LC-DB phases are specially deactivated for basic compounds. These columns provide good peak shape and high efficiency for organic bases.
Supelcosil™ ABZ+Plus is a polar-embedded phase with high deactivation and unique selectivity. ABZ+Plus enables high efficiency separations of acids, bases, zwitterions and other difficult compounds.
Supelcosil™ LC-18-S, LC-18-T and LC-PAH are application-specific columns for the analysis of nucleosides, nucleotides or polyaromatic hydrocarbons.
With the Supelcosil Hisep, there is also a mixed-mode column that possesses a shielded hydrophobic phase. Here, the silica-gel is coated by a thin polymer layer with hydrophobic regions in a hydrophilic network. Thus, small analytes can be retarded and proteins are excluded.
Phase-Name | Modification | Particle Size | Pore Size | End-capping | C-Content | USP | Surface / m2/g | pH-Range | Tmax |
Supelcosil™ LC-18 | C18 | 3, 5, 12 µm | 120 Å | + | 11% | L1 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-18 DB | C18 | 3, 5 µm | 120 Å | + | 11% | L1 | 170 | N/A | N/A |
Supelcosil™ LC-18-S | C18 | 5 µm | 120 Å | + | 11% | L1 | 170 | N/A | 70 °C |
Supelcosil™ LC-18-T | C18 | 3, 5 µm | 120 Å | + | 12.3% | L1 | 170 | N/A | 70 °C |
Supelcosil™ LC-8 | C8 | 3, 5 µm | 120 Å | + | 6% | L7 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-8 DB | C8 | 3, 5 µm | 120 Å | + | 6% | L7 | 170 | N/A | N/A |
Supelcosil™ LC-1 | C1 | 5 µm | 120 Å | + | 2% | L13 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-DP | Diphenyl | 5 µm | 120 Å | + | 6% | L11 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-CN | Cyanopropyl | 3, 5 µm | 120 Å | + | 4% | L10 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-PCN | Cyanopropyl | 5 µm | 120 Å | + | 4% | L10 | 170 | N/A | N/A |
Supelcosil™ LC-NH2 | Aminopropyl | 3, 5 µm | 120 Å | + | 3% | L8 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-NH2-NP | Aminopropyl | 5 µm | 120 Å | + | 3% | L8 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-Diol | Diol | 5 µm | 120 Å | - | 3.5% | L20 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-F | Pentafluorophenyl | 5 µm | 120 Å | + | 5% | L43 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ ABZ+Plus | Alkylamide | 5 µm | 120 Å | + | 12% | L60 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ ABZ | Alkylamide | 3, 5, 12 µm | 120 Å | + | 12% | L60 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ Suplex™ pKb-100 | Alkylamide | 5 µm | 120 Å | - | 12.5% | N/A | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ SAX1 | Propyltrimethylammonium | 5 µm | 120 Å | N/A | 12% | L14 | 170 | N/A | N/A |
Supelcosil™ LC-SCX | Propylsulfonic acid | 5 µm | 120 Å | N/A | N/A | L9 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ LC-PAH | C18 | 3, 5 µm | 120 Å | N/A | N/A | N/A | N/A | N/A | N/A |
Supelcosil™ LC-Si | - | 3, 5, 12 µm | 120 Å | - | - | L3 | 170 | 2.0‒7.5 | 70 °C |
Supelcosil™ Hisep | Shielded hydrophobic phase | 5 µm | 120 Å | N/A | N/A | N/A | 170 | N/A | 70 °C |
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