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Merck-Supelcoâ„¢ (Sigma-Aldrichâ„¢) is manufacturer of some special HPLC columns for the separation of enantiomers developed by Astec in collaboration with Prof. D. Armstrong of the University of Texas at Arlington. Since 2006 Astec is part of Sigma-Aldrichâ„¢ (Merck). Astec covers a broad range of chemistries, enantioselectivity and application focus.