Macherey-Nagel / Nucleosil

Nucleosil

Nucleosil^® is a family of totally porous spherical silicas, manufactured by Macherey-Nagel. They feature a very pure and uniform SiO₂ structure and have gained wide acceptance as routine chromatographic packings for very different fields of modern chromatography. Nucleosil^® was developed in the 1970s and was one of the first spherical silicas used in HPLC. Nowadays it is a world-renowned HPLC packing. The phases are available with many different modifications.

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Nucleosil 300 OH 7µm 100x4,0mm HPLC Column

MZ3357-100040

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.0 mm Length: 100 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 75x4,0mm HPLC Column

MZ3357-075040

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.0 mm Length: 75 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 60x4,0mm HPLC Column

MZ3357-060040

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.0 mm Length: 60 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 50x4,0mm HPLC Column

MZ3357-050040

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.0 mm Length: 50 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 40x4,0mm HPLC Column

MZ3357-040040

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.0 mm Length: 40 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 33x4,0mm HPLC Column

MZ3357-033040

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.0 mm Length: 33 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 20x4,0mm HPLC Column

MZ3357-020040

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.0 mm Length: 20 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 250x3,0mm HPLC Column

MZ3357-250030

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 3.0 mm Length: 250 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 200x3,0mm HPLC Column

MZ3357-200030

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 3.0 mm Length: 200 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

Nucleosil 300 OH 7µm 150x3,0mm HPLC Column

MZ3357-150030

Product Type: HPLC Column Bet Surface Area [m2/g]: 100.0 Carbon Load: 1.5 % Delivery Time: approx. 1-2 days Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: MZ-Analysentechnik Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 3.0 mm Length: 150 mm Particle Morphology: spherical, fully porous pH Minimum: 2.0 pH Maximum: 8.0 Pressure Stability: 300 bar Pore Size: 300 Å Technology: HPLC Temperature Maximum [°C]: 60 USP Class: L20

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Technical Data

Phase-Name	Modification	Particle Size	Pore Size	End-capping	C-Content	USP	Surface	pH-Range	Tmax
Nucleosil^® C₁₈	C₁₈	5 µm 3, 5, 7, 10 µm 3, 5, 7, 10 µm 5 µm 7 µm 7 µm	50 Å 100 Å 120 Å 300 Å 500 Å 1000 Å	+	14.5% 15% 11% 6.5% 2% 1%	L1	420 m2/g 350 m2/g 200 m2/g 100 m2/g 35 m2/g 25 m2/g	2.0‒8.0	N/A
Nucleosil^® C₁₈AB	C₁₈	5 µm	100 Å	+	25%	L1	350 m²/g	1.0‒9.0	N/A
Nucleosil^® C₁₈HD	C₁₈	3, 5 µm	100 Å	+	20%	L1	350 m²/g	2.0‒9.0	N/A
Nucleosil^® 100-5 C₁₈PAH	C₁₈	5 µm	100 Å	N/A	N/A	L1	350 m²/g	N/A	N/A
Nucleosil^® C₈	C₈	5, 7, 10 µm 3, 5 µm 5µm	100 Å 120 Å 300 Å	-	8.5% 6.5% 3 %	L7	350 m2/g 200 m2/g 100 m2/g	2.0‒8.0	N/A
Nucleosil^® C₈ec	C₈	5 µm	100 Å	+	9%	L7	350 m²/g	2.0‒8.0	N/A
Nucleosil^® C₈HD	C₈	5 µm	100 Å	+	13%	L7	350 m²/g	2.0‒8.0	N/A
Nucleosil^® C₄	C₈	5 µm	120 Å 300 Å	+	4% 2%	L26	200 m2/g 100 m2/g	2.0‒8.0	N/A
Nucleosil^® C₂	Dimethyl	7 µm	100 Å	-	3.5%	L16	350 m²/g	2.0‒8.0	N/A
Nucleosil^® C₆H₅	Phenylpropyl	5, 7 µm	100 Å	-	8%	L11	350 m²/g	2.0‒8.0	N/A
Nucleosil^® CN/CN-RP	Cyanopropyl	5, 10 µm 7 µm	100 Å 120 Å	-	5% 3%	L10	350 m²/g 200 m²/g	2.0‒8.0	N/A
Nucleosil^® NH₂/ NH₂-RP	Aminopropyl	3, 5, 10 µm	100 Å	-	3.5%	L8	350 m²/g	2.0‒8.0	N/A
Nucleosil^® OH	Diol	5 µm	100 Å	-	N/A	L20	350 m²/g	2.0‒8.0	N/A
Nucleosil^® C₁₈Nautilus	Polar embedded C₁₈	3, 5 µm	100 Å	+	16%	L60	350 m²/g	2.0‒8.0	N/A
Nucleosil^® Protect I	Polar embedded Alcyl	5 µm	100 Å	+	11%	N/A	350 m²/g	2.0‒8.0	N/A
Nucleosil^® SB	‒N⁺(CH₃)₃ Cl⁻	5, 10 µm	100 Å	-	10%	L14	350 m²/g	2.0‒8.0	N/A
Nucleosil^® Anion II	Quaternary Ammonium	10 µm	300 Å	N/A	N/A	N/A	100 m²/g	2.0‒7.5	N/A
Nucleosil^® N(CH₃)₂	Diethylamino	5 µm	100 Å	-	4%	N/A	350 m²/g	2.0‒8.0	N/A
Nucleosil^® SA	Benzenesulfonic acid	5, 10 µm	100 Å	-	6,5%	L9	350 m²/g	2.0‒8.0	N/A
Nucleosil^® MPN	C₁₈ C₄	5 µm	100 Å 300 Å	N/A	N/A	L1 L26	350 m²/g 100 m²/g	2.0‒8.0	N/A
Nucleosil^® PPN	C₁₈	5 µm	100 Å 500 Å	N/A	N/A	L1	350 m²/g 35 m²/g	1.0‒9.0	N/A
Nucleosil^® Carbohydrate	Amino	10 µm	N/A	N/A	N/A	L8	N/A	N/A	N/A
Nucleosil^® CHIRAL-1	L-Hydroxyproline Cu2+ complex	5 µm	120 Å	N/A	N/A	L32	200 m²/g	N/A	N/A
Nucleosil^® CHIRAL-2	N-(3,5-Dinitrobenzoyl)-D-phenylglycin	5 µm	100 Å	N/A	N/A	L36	350 m²/g	N/A	N/A
Nucleosil^® CHIRAL-3	N-(3,5-Dinitrobenzoyl)-L-phenylglycin	5 µm	100 Å	N/A	N/A	L36	350 m²/g	N/A	N/A
Nucleosil^® SiOH	-	5 µm	50 Å 100 Å	-	-	L3	450 m²/g 350 m²/g	2.0‒8.0	N/A

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