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Ultrasphere® HPLC Columns, formerly manufactured by Beckman Coulter, are part of Hichrom™ Limited since 2010. Hichrom™ continues to manufacture the full range of genuine columns and media to the same exacting manufacturing protocols and specifications. Ultrasphere® was one of the earliest commercially available spherical silicas. Ultrasphere columns remain widely referenced within both industry and academia and are recognised to provide excellent chromatographic performance. Five different modifications are available.