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ProteoSil
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The latest column series from GL Sciences are the ProteoSil columns. The ProteoSil columns have been specially developed for the requirements of the biopharmaceutical market.
As biopharmaceuticals are much larger than conventional pharmaceuticals, the ProteoSil columns have a pore size of 100, 200 and 300Å, optimised for this analysis. Due to possible interactions of the samples with the hardware, all columns are available with bioinert PEEK lined stainless steel, PEEK or stainless steel to meet all requirements. The small solder to solder differences also make these columns ideal for LC/MS applications.
The ProteoSil columns are available with different modifications and for different chromatographic mechanisms such as reverse phase, HILIC and SEC. Additionally, 1.9µm particles are available for UHPLC applications.
Product Line
- Inertsil
- InertSustain
- InertSustain Swift
- InertCap
- InertSep
- Titansphere
- LD239 Gas Leak Detector
- GF-1010 Digital Gas Flow Meter
- Bioptic
- GL Sciences-HayeSep
- GL Sciences-Porapak
- GL Sciences-TC
- GL Sciences-Tenax
- GL Sciences-Unibeads
- InertCore
- InertSep WAX FF/GCB
- InertSphere
- MonoCap
- MonoFas
- MonoSpin
- MonoTrap
- OPTIC
- ProteoSil
- SYPRON
Technical Data
| Phase | Modification | Particle size | Pore size | Molecular weight | Target components |
| ProteoSil 100-C18 | C18 | 1.9, 3, 5 µm | 100 Å | <5,000 Da | Proteins/peptides; oligonucleotides/nucleic acids |
| ProteoSil 200-C18 | C18 | 1.9, 3, 5 µm | 200 Å | 5,000-20,000 Da | Proteins/peptides; oligonucleotides/nucleic acids |
| ProteoSil 300-C18 | C18 | 5 µm | 300 Å | >20,000 Da | Proteins/peptides; oligonucleotides/nucleic acids |
| ProteoSil 200-C8 | C8 | 1.9, 3, 5 µm | 200 Å | 5,000-20,000 Da | Proteins/peptides; oligonucleotides/nucleic acids |
| ProteoSil 300-C8 | C8 | 5 µm | 300 Å | >20,000 Da | Proteins/peptides; oligonucleotides/nucleic acids |
| ProteoSil 300-C4 | C4 | 5 µm | 300 Å | >20,000 Da | Proteins/Peptides; Monoclonal antibodies; Oligonucleotides/Nucleic acids |
| ProteoSil HILIC | Amide | 1.9, 3, 5 µm | 100 Å |
| Proteins/Peptides; Monoclonal antibodies |
| ProteoSil 100-SEC | Diol | 5 µm | 100 Å | <5,000 Da | Proteins/Peptides; Monoclonal antibodies; Oligonucleotides/Nucleic acids |
| ProteoSil 300-SEC | Diol | 5 µm | 300 Å | 5,000-600,000 Da | Proteins/Peptides; Monoclonal antibodies; Oligonucleotides/Nucleic acids |
What characterises the ProteoSil range?
- High reproducibility from batch to batch
- Carefully designed pore size to fulfil the requirements for biopharmaceutical separations
- Bioinert hardware available
When do you benefit from the ProteoSil columns?
You can benefit from ProteoSil columns if a slightly larger pore size than the usual 100 or 120 Å is required. These larger pores allow some analytes to be better separated.
Conclusion: ProteoSil columns are ideal for the biopharmaceutical market. With the different pore sizes of 100, 200 and 300 Å, a wide range of biomolecules can be separated.
Downloads
Brochures
GL-Sciences ProteoSil - MonoSelect Bioseparation Solution Bio LC Columns
Applications
GL-Sciences ProteoSil Applications
The right column for you - we will be happy to support you individually
Competent consultants are always at your side. Write a message to our consultants, we will get back to you and give you individual support.
You will find:
Application support
Availability and delivery times
Price information with individual conditions
Certificates of analysis, MSDS, data sheets