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ReproSil Chiral
ReproSil Chiral HPLC column exist with different chiral selectors based on polysaccharides, Pirkle phases, proteins and cyclodextrins. There are also some phases available which are unique.
Technical Data
| Phase | Modification | Particle size / μm | USP Code |
| NR | Pirkle brush type | 3, 5, 8, 12 | N/A |
| NR-R | Pirkle brush type | 8, 12 | N/A |
| AM | Amylose tris-(3,5-dimethylphenyl) carbamate | 3, 5, 10, 20 | L51 |
| AM-R | Amylose tris-(3,5-dimethylphenyl) carbamate | 3, 5, 10 | L51 |
| OM | Cellulose tris-(3,5-dimethylphenyl) carbamate | 3, 5, 10, 20 | L40 |
| OM-R | Cellulose tris-(3,5-dimethylphenyl) carbamate | 3, 5, 10 | L93 |
| AMS | Amylose tris (S)-a-methylbenzyl carbamate | 3, 5, 10 | L90 |
| AMS-R | Amylose tris (S)-a-methylbenzyl carbamate | 3, 5 | N/A |
| CM | Cellulose Tris-phenyl carbamate | 3, 5, 10 | L70 |
| GM | Cellulose tris (4-methyl-phenyl) carbamate | 5 | N/A |
| JM | Cellulose tris (4-methylbenzoyl) carbamate | 3, 5, 10 | L80 |
| JM-R | Cellulose tris (4-methylbenzoyl) carbamate | 3, 5, 10 | L107 |
| BM | Cellulose (tris-benzoyl) carbamate | 5 | N/A |
| ZM | Cellulose tris-(3-chloro-4-methylphenyl)-carbamate | 3, 5 | N/A |
| XM | Cellulose tris-(4-chloro-3-methylphenyl)-carbamate | 3, 5 | N/A |
| ZA | Amylose tris-3-(chloro-4-methylphenyl) carbamate | 3, 5 | N/A |
| YM | Amylose tris-(5-chloro-2-methylphenyl)-carbamate | 5 | N/A |
| MIB | Cellulose tris-(3,5-dimethylphenyl)-carbamate | 5 | N/A |
| MIC | Cellulose tris-(3,5-dichlorophenyl) carbamate | 3, 5 | N/A |
| MIX | Cellulose tris-(4-chloro-3-methylphenyl)-carbamate | 5, 10 | N/A |
| MIZ | Cellulose tris-(3-chloro-4-methylphenyl) carbamate | 3, 5, 10 | N/A |
| MOF | Cellulose tris-(4-chlorophenyl) carbamate | 5 | N/A |
| MIA | Amylose tris-(3,5-dimethylphenyl) carbamate | 5 | N/A |
| MIF | Amylose tris-(3-chloro-4-methylphenyl) carbamate | 5 | N/A |
| MID | N/A | 5 | N/A |
| AGP | α1-acid glycoprotein | 5 | L41 |
| HSA | human serum albumin | 5 | L79 |
| PS | N/A | 8 | N/A |
| OH | N/A | 8 | N/A |
| AA | N/A | 5, 8 | L63 |
| TAG | Teicoplanin Aglycon | 5, 8, 10 | L63 |
| CA | N/A | 5, 8 | N/A |
| TG | N/A | 5 | N/A |
| Beta-CD-R(+) phenylethylamine | N/A | N/A | N/A |
| Chirobiotic-TAG | Teicoplanin Aglycon | 10 | L63 |
| L-PhenylGlycine | N-(3,5-dinitrobenzoyl)-L-phenylglycine | 5 | L36 |
| D-phenylglycine | N-(3,5-dinitrobenzoyl)-D-phenylglycine | 3, 5 | L36 |
| L-leucine | N-(3,5-dinitrobenzoyl) L-leucine | 5 | N/A |
| L-proline | L-proline | 5 | N/A |
| L-hydroxy-proline | L-hydroxy-proline | 5 | L32 |
| Beta-CD | Beta-cyclodextrin | 5 | L45 |
| Beta-PM | Beta-cyclodextrin | 5 | L45 |
ReproSil Chiral-NR: Is suitable for the separation of aromatics, amides, carbamates, esters, alkylamines and compounds with multiple stereocentres in the normal phase.
ReproSil Chiral-AM: Is suitable for the separation of aromatics, amides, carbamates, esters, alkylamines and compounds with multiple stereocentres in the normal phase.
ReproSil Chiral-OM: Can be used if ReproSil Chiral-AM cannot completely separate the compounds; especially suitable for beta-blockers, compounds with similar functionalities and steroids.
ReproSil Chiral-AMS: If no separation can be achieved with ReproSil Chiral-AM, this phase should be used; especially suitable for β-lactams, glycidol derivates, epoxides, acids, natural products and heterocyclic compounds.
ReproSil Chiral-CM: Can be used if no separation can be achieved with ReproSil Chiral-Am or -OM.
ReproSil Chiral-GM: Special column for compounds which are only partially separated by ReproSil Chiral-OM and -CM.
ReproSil Chiral-JM: Especially suitable for the following compounds (or substances with similar structure): ibuprofen, ketamine, methadone, nicotine, steroids, acebutolol, albuterol, chlophedianol, mianserine and other compounds with a large substituent at the chiral centre.
ReproSil Chiral-BM: Is suitable for separations which are not sufficient with ReproSil Chiral-AMS or -JM.
ReproSil Chiral-AGP/-HSA: This phase is used in reversed phase; retention and enantioselectivity can be adjusted by pH, buffer concentration and an organic modifier.
ReproSil Chiral-PS: Is suitable for separation in normal- or reversed phase of aromatic compounds which contain sulfur or phosphorous.
ReproSil Chiral-OH: For aromatic alcohols with an OH group near the chiral centre.
ReproSil Chiral-AA: Special phase for amino acids (L-form elutes first).
ReproSil Chiral-TAG: Suitable for amino alcohols, N-blocked amino acids, α-hydroxy acids, oxazolidinones, hydantoins, imides and amino acids.
ReproSil Chiral-CA: Pirkle phase compatible with reversed phase for carboxyl groups near the chiral centre.
ReproSil Chiral-TG: Reversed phase with terguride for chiral FMOC- and dansyl amino acids.
ReproSil Chiral-L-PhenylGlycin: Brush-type phase for herbicides and pharmaceuticals.
ReproSil Chiral-L-Prolin: Davanako ligand exchange phase for amino acids, hydantiones, succinimides, gluthetimides, barbiturates and sulfoxides.
ReproSil L-Hydroxy-Prolin: Ligand exchange phase with copper sulfate.
Downloads
Brochures
Dr. Maisch Chiral Columns Catalogue
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