Polymer Columns

Polymers as filling materials in liquid chromatography are characterised by their exceptional chemical and mechanical stability. Compared to silica, they are more resistant to high pH values and aggressive solvents, which makes them particularly favourable for applications where such conditions are required. This stability extends the lifetime of the column and reduces the overall cost of laboratory operations. In addition, polymers allow a wider range of samples to be analysed, including those that would be incompatible with silica-based columns. Their versatility includes ion exchange chromatography, exclusion chromatography and reversed phase chromatography, with specialised polymers developed to achieve optimal separation performance for specific classes of molecules.

 

Learn the basics here and get an overview of manufacturers on the international chromatography market that produce polymer-based HPLC and GPC columns. We will be happy to advise you on the selection of the right polymer-based chromatography column for your application!

Basics

Which polymers are used?

The hydrophilic base materials used include polyvinyl alcohol (see Figure 1), polymethacrylic acid ester or polyhydroxymethacrylic acid ester. Styrene-divinylbenzene copolymer is usually used as a hydrophobic base material.

What are the advantages of polymer-based HPLC columns?

  • High thermal and chemical stability
  • Can be used within a wide pH range (approx. 2 to 12, in some cases also from 1 to 14)
  • Absence of free silanols and heavy metal ions
    • Undesirable interactions of the analytes with the stationary phase are avoided
    • High recovery rates
  • Long service life
  • Available for almost any separation technique (e.g. RP- or NP-HPLC, HILIC, HIC, IC,...)

MZ-Analysentechnik GmbH gives you access to an extensive range of polymer-based HPLC columns. We will be happy to provide you with a customised quotation for your requirements so that you can compare the prices and delivery times of the individual manufacturers or simply look directly at the individual manufacturer profiles, where you will find the entire product range for filtering.

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