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Cannabinoids
Cannabinoids are a group of natural substances, of which over 100 different representatives are known to date. These substances are mainly found in the hemp plant (cannabis plant). Tetrahydrocannabinol (THC), probably the best-known representative of this class of substances, has a psychoactive and intoxicating effect in the human body, as do some other cannabinoids. The use of cannabinoids for medical purposes has been possible in Germany since 1 March 2017. Nevertheless, cannabinoids are subject to the Narcotics Act, as there is an increased risk of these substances being abused as drugs due to the effects mentioned above. The legalisation of cannabis is the subject of controversial debate, but is increasingly coming into focus. The global market is constantly growing.
The use of cannabinoids for medical purposes requires robust and reliable methods for the production and analysis of these substances. Using high-performance liquid chromatography (HPLC), both natural and synthetic cannabinoids can be separated and analysed quickly and reliably. HPLC columns with a C18-modified stationary phase are often used for this purpose.
Applications
Separation of 18 Cannabinoids with AMT HALO LPH C18
Peak identities
1. Cannabidivarinic acid (CBDVA) 2. Cannabidivarin (CBDV) 3. Cannabidiolic acid (CBDA) 4. Cannabigerolic acid (CBGA) 5. Cannabigerol (CBG) 6. Cannabidiol (CBD) 7. Tetrahydrocannabivarinic acid (THCV) 8. Tetrahydrocannabivarinic acid (THCVA) 9. Cannabinol (CBD) Cannabidiol (CBD) 7. Tetrahydrocannabivarin (THCV) 8. Tetrahydrocannabivarinic acid (THCVA) 9. Cannabinol (CBN) 10. Cannabinolic acid (CBNA) 11. Exo-tetrahydrocannabinol (EXO-THC) 12. delta 9- Tetrahydrocannabinol (D9-THC) 13. delta 8- Tetrahydrocannabinol (D8-THC) 14. Cannabicycol (CBL) 15. Cannabichromene (CBC) 16. Tetrahydrocannabinolic acid A (THCA-A) 17. Cannabichromenic acid (CBCA) 18. Cannabicyclic acid (CBLA)
Downloads
Manufacturer overview
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AMT
HPLC - Reversed Phase:
- HALO 90Å C18, 2.7µm
- HALO 90Å LPH-C18, 2.7µm
- HALO 90Å C18, 1.5mm ID, 2.7µm
Avantor ACE
HPLC - Reversed Phase
- ACE Excel C18-AR, 3 µm
- ACE Excel C18-AR, 2 µm
- ACE Excel SuperC18, 2µm
- ACE UltraCore SuperC18, 2.5µm
- ACE Excel C18, 1.7µm
Nouryon - Kromasil
HPLC - Reversed Phase:
- Kromasil 100 C18, 5µm
UCT
HPLC - Reversed Phase:
- Selectra DA, 3µm
- Selectra Aqueous C18, 3µm
Sample preparation:
- Enviro-Clean
- Enviro-Clean dSPE
- QuEChERS
The right column for you - we will be happy to support you individually
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