In chromatography,organic standards are reference materials used for calibration, quality control and validation of analytical methods. These standards consist of high-purity organic compounds with precisely known concentrations and are crucial for the precise and reliable analysis of samples containing organic substances.
There are different types of organic standards that are used depending on the application and specific requirements:
- Single standards: These standards consist of a single organic compound at a known concentration. They are often used to calibrate and validate specific analytes.
- Mixed standards: Mixed standards contain several organic compounds in known concentrations. They are used to facilitate the simultaneous analysis of several analytes and to increase the efficiency of calibration.
- Isotope labelled standards: These standards contain isotopically labelled versions of the analytes. They are particularly useful as internal standards as they have similar chemical properties to the analytes but can be easily distinguished due to their isotopically labelled nature.
- Matrix-matched standards: These standards are dissolved in a matrix that is similar to the sample being analysed. They are used to take matrix effects into account and improve the accuracy of the analyses.