Waters / BioResolve

BioResolve

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BioResolve

BioResolve columns from Waters are HPLC and UHPLC columns for the analysis of biomolecules and in particular mAb-based and related biotherapeutics. Three different modifications are available for different applications:

BioResolve RP mAb Polyphenyl: Polyphenyl modification for reversed-phase chromatography; material based on fused-core technology; for the analysis of intact and IdeS-digested mAbs
BioResolve SCX mAb: cation exchange modification; material is non-porous polymer according to L34; for the analysis of antibody charge variants
BioResolve SEC mAb : size exclusion modification; fully porous hybrid material; for the analysis of mAb aggregates (HMWS), monomers and fragments (LMWS)

Product Line

Products

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BioResolve RP mAb Polyphenyl Method Validation Kit, 450A, 2.7 um, 1mm X 100mm, 3/pkg with Intact mAb and mAb Subunit Standards

176004288

€3,150.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Capillary Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 1.0 mm Length: 100 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl VanGuard Cartridge w/holder, 450Å, 2.7 µm, 2.1 mm x 5 mm, 3/pkg

176004212

€660.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 2.1 mm Length: 5 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl Column, 450A, 2.7 um, 1mm X 150mm, 1/pkg with Intact mAb and mAb Subunit Standards

176004210

€1,160.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Capillary Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 1.0 mm Length: 150 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl Column, 450A, 2.7 um, 1mm X 100mm, 1/pkg with Intact mAb and mAb Subunit Standards

176004209

€1,050.00

BioResolve RP mAb Polyphenyl Column, 450A, 2.7 um, 1mm X 50mm, 1/pkg with Intact mAb and mAb Subunit Standards

176004208

€1,010.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Capillary Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 1.0 mm Length: 50 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 4.6 mm x 150 mm, 3/pkg

176004171

€3,470.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.6 mm Length: 150 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 4.6 mm x 100 mm, 3/pkg

176004170

€3,150.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.6 mm Length: 100 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm x 150 mm, 1/pkg w/ Intact mAb and mAb Subunit Stds

176004169

€1,160.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.6 mm Length: 150 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm x 100 mm, 1/pkg w/ Intact mAb and mAb Subunit Stds

176004168

€1,050.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.6 mm Length: 100 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm x 50 mm, 1/pkg w/ Intact mAb and mAb Subunit Stds

176004167

€1,010.00

Product Type: (U)HPLC Column Kit Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 4.6 mm Length: 50 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

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Technical Data

Phase	Modification	Particle size	Pore size	Surface area	C-content	Endcapped	USP	pH range
BioResolve mAb Polyphenyl	Phenyl	2.7 µm	450 Å	N/A	N/A	+	L11	1.0-8.0
BioResolve SCX mAb	N/A	3 µm	non-porous	N/A	N/A	+	L34	2.0-7.0
BioResolve SEC mAb	Diol	2.5 µm	200 Å	220 m²/g	12 %C	-	L20, L33, L59	2.5-8.0

Downloads

Brochures

HPLC SEC Sample Preparation
Waters Catalog 23-24 Biomolecule HPLC SEC SPE Brochure
SEC Standards
Waters Catalog 23-24 SEC Columns Standards SEC Brochure

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