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BioResolve

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BioResolve

BioResolve columns from Waters are HPLC and UHPLC columns for the analysis of biomolecules and in particular mAb-based and related biotherapeutics. Three different modifications are available for different applications:

BioResolve RP mAb Polyphenyl: Polyphenyl modification for reversed-phase chromatography; material based on fused-core technology; for the analysis of intact and IdeS-digested mAbs
BioResolve SCX mAb: cation exchange modification; material is non-porous polymer according to L34; for the analysis of antibody charge variants
BioResolve SEC mAb : size exclusion modification; fully porous hybrid material; for the analysis of mAb aggregates (HMWS), monomers and fragments (LMWS)

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BioResolve RP mAb Polyphenyl Column, 450A, 2.7 um, 2.1mm X 50mm, 1/pkg

186008944

€1,010.00

Product Type: (U)HPLC Column Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 2.1 mm Length: 50 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 2.0 pH Maximum: 7.0 Pressure Stability: 689 bar Pore Size: 450 Å Technology: U(H)PLC Temperature Minimum [°C]: 50 Temperature Maximum [°C]: 90

BioResolve RP mAb Polyphenyl VanGuard Cartridge, 450A, 2.7 um, 2.1mm X 5mm, 3/pkg

186008943

€530.00

Product Type: HPLC Guard Cartridges Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Phenyl Column Type: Analytical Column Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Silica Internal Diameter: 2.1 mm Length: 5 mm Particle Morphology: spherical, solid core, porous shell pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 450 Å

BioResolve SEC mAb Method Validation Kit, 200Å, 2.5 µm, 7.8 x 300 mm, 3/pk with mAb Size Variant Standard;

176004642

€10,800.00

Product Type: SEC/GPC Column Kit Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 7.6 mm Length: 300 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Method Validation Kit, 200Å, 2.5 µm, 7.8 x 150 mm, 3/pk with mAb Size Variant Standard;

176004641

€7,450.00

Product Type: SEC/GPC Column Kit Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 7.6 mm Length: 150 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Method Validation Kit, 200Å, 2.5 µm, 4.6 x 300 mm, 3/pk with mAb Size Variant Standard;

176004640

€10,300.00

Product Type: SEC/GPC Column Kit Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 4.6 mm Length: 300 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Method Validation Kit, 200Å, 2.5 µm, 4.6 x 150 mm, 3/pk with mAb Size Variant Standard;

176004639

€6,910.00

Product Type: SEC/GPC Column Kit Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 4.6 mm Length: 150 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 7.8 x 300 mm, 1/pk with mAb Size Variant Standard;

176004599

€3,710.00

BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 7.8 x 150 mm, 1/pk with mAb Size Variant Standard;

176004598

€2,690.00

Product Type: SEC/GPC Column Kit Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 7.6 mm Length: 150 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 4.6 x 300 mm, 1/pk with mAb Size Variant Standard;

176004597

€3,550.00

Product Type: SEC/GPC Column Kit Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 4.6 mm Length: 300 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 4.6 x 150 mm, 1/pk with mAb Size Variant Standard;

176004596

€2,530.00

Product Type: SEC/GPC Column Kit Bet Surface Area [m2/g]: 220.0 Carbon Load: 12.0 % Delivery Time: approx. 5 days (product only available in Germany) Chemistry: Diol Column Type: Analytical Column Endcapping: non endcapped Manufacturer: Waters Hardware Type: Ready-to-use Column Matrix: Hybrid Internal Diameter: 4.6 mm Length: 150 mm Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 8.0 Pore Size: 200 Å Technology: U(H)PLC USP Class: L33

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Technical Data

Phase	Modification	Particle size	Pore size	Surface area	C-content	Endcapped	USP	pH range
BioResolve mAb Polyphenyl	Phenyl	2.7 µm	450 Å	N/A	N/A	+	L11	1.0-8.0
BioResolve SCX mAb	N/A	3 µm	non-porous	N/A	N/A	+	L34	2.0-7.0
BioResolve SEC mAb	Diol	2.5 µm	200 Å	220 m²/g	12 %C	-	L20, L33, L59	2.5-8.0

Downloads

Brochures

HPLC SEC Sample Preparation
Waters Catalog 23-24 Biomolecule HPLC SEC SPE Brochure
SEC Standards
Waters Catalog 23-24 SEC Columns Standards SEC Brochure

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