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Thermo Scientific / MabPac

MabPac

MAbPac™ is a family of HPLC columns, manufactured by Thermo Scientific™, for efficient analysis of monoclonal antibodies and their fragments and aggregates using different separation techniques.
 

MAbPac™ RP is an HPLC column for high resolution accurate mass determination of monoconal antibody variants, antibody drug conjugates (ADC) and proteins by reversed-phase chromatography. The columns are based on polyvinylbenzene and exhibit superior pH and temperature stability.
 

MAbPac™ SEC-1 is a size exclusion chromatography (SEC) column specifically designed for the high-resolution separation and characterization of monoclonal antibodies (mAbs) and their aggregates. The separation range for globular proteins is about 10.000 to 1.000.000 g/mol.
 

The MAbPac™ HIC column family is designed for separations of monoclonal antibodies (mAb´s) and related biologics by Hydrophobic Interaction Chromatography (HIC). The base material for MAbPac™ HIC-10 and HIC-20 is porous silica gel and for MAbPac™ HIC-butyl it is a hydrophilic polymer.
 

MAbPac™ SCX-10 is a strong cation exchange column designed specifically for the high-resolution, high efficiency charged variant analysis of monoclonal antibodies and associated variants. MabPac™ SCX-10 RS is designed for higher flow rates and high throughput analysis.
 

MAbPac™ Protein A is an affinity column designed to provide fast monoclonal antibody (mAb) titer analysis. The column is based on a non-porous polymeric resin consisting of a divinylbenzene core and a hydrophilic surface. The recombinant Protein A ligands are covalently attached onto the hydrophilic resin surface. The binding capacity is about 3.5 mg IgG/g Resin.

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SP Prep ColumnOD Column MP SCX-10 4x250 3COL 1LOT
TFS-SP6864
MabPac SCX-10 3µm 4x50mm
TFS-077907
MabPac HIC-20 5µm 250mm x 50mm ID
TFS-02005-259570
MabPac RP analytical 4µM 1.0x150mm
TFS-303184
MabPac RP analytical 4µM 1.0x100mm
TFS-303183
MabPac RP analytical 4µM 1.0x100mm
TFS-302695
MabPac RP analytical 4µM 1.0 x 150mm
TFS-302598
MabPac RP analytical 4µM 1.0 x 50mm
TFS-302597
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Items 61-68 of 68

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Technical Data

Phase-Name

Modification

Particle Size

Pore Size

End-capping

C-Content

USP

Surface

pH-Range

Tmax

MAbPac™ RP

-

4 µm

1500 Å

-

N/A

N/A

N/A

0.0‒14.0

110 °C

MAbPac™
SEC-1

Diol

5 µm

300 Å

N/A

N/A

N/A

N/A

2.5‒7.5

30 °C

MAbPac™
HIC-10

Proprietary Polyamide

5 µm

1000 Å

N/A

N/A

N/A

20 m2/g

2.0‒8.0

60 °C

MAbPac™
HIC-20

Proprietary Amide

5 µm

1000 Å

N/A

N/A

N/A

20 m2/g

2.0‒9.0

60 °C

MAbPac™
HIC-Butyl

Butyl

5 µm

Non-porous

N/A

N/A

N/A

N/A

2.0‒12.0

60 °C

MAbPac™
SCX-10

Sulfonic acid

3, 5, 10 µm

Non-porous

N/A

N/A

N/A

N/A

2.0‒12.0

60 °C

MAbPac™
SCX-10 RS

Sulfonic acid

5 µm

Non-porous

N/A

N/A

N/A

N/A

2.0‒12.0

60 °C

MAbPac™
Protein A

Protein A

12 µm

Non-porous

N/A

N/A

N/A

N/A

2.5‒7.5

30 °C

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