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With the Evokeâ„¢ product line, Regis Technologies offers C18 columns for efficient and reproducible separations using reversed-phase chromatography. The material is based on high purity silica, which is endcapped using a unique vapour phase process. The result is a highly inert, hydrophobic surface with a large carbon coverage. This means that higher concentrations of organic solvents can be used, which can be particularly advantageous for electrospray ionisation or preparative applications.