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Astec Cyclobond
Merck-Supelco™ (Sigma-Aldrich™) is manufacturer of some special HPLC columns for the separation of enantiomers developed by Astec in collaboration with Prof. D. Armstrong of the University of Texas at Arlington. Since 2006 Astec is part of Sigma-Aldrich™ (Merck).
The Astec Cyclobond® family comprises highly enantioselective chiral HPLC stationary phases based on cyclodextrins that have been bonded through covalent ether linkages to spherical, high purity silica particles.
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Technical Data
| Phase-Name | Modification | Particle Size | Pore Size | End-capping | C-Content | USP | Surface | pH-Range | Tmax |
| Astec Cyclobond® I 2000 | Underivatized, native β-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® I 2000 AC | Acetylated β-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® I 2000 DM | Dimethylated β-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® I 2000 DMP | 3,5-Dimethylphenyl carbamate modified β-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® I 2000 DNP | Dinitrophenyl modified β-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® I 2000 HP-RSP | (R,S)-Hydroxypropyl modified β-Cyclodextrin (high performance) | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® I 2000 RSP | (R,S)-Hydroxypropyl modified β-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® I 2000 SP | (S)-Hydroxypropyl modified β-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | L45 | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® II | Underivatized, native γ-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | N/A | N/A | 3.0−7.0 | N/A |
| Astec Cyclobond® II AC | Acetylated γ-Cyclodextrin | 5, 10 µm | 100 Å | N/A | N/A | N/A | N/A | 3.0−7.0 | N/A |
Downloads
Applications
Merck Supelco Applications-Notebook Vol1 HPLC, UHPLC, LC-MS, SFC, SPE
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