Merck Supelco (Sigma-Aldrich) / Astec Chiraldex

Astec Chiraldex

Astec Chiraldex^® are special GC columns, manufactured by Merck-Supelco™ (Sigma-Aldrich™) for the separation of enantiomers. The phases are based on differently modified cyclodextrins as the chiral selector.

20% Discount on Supelco Ascentis HPLC Columns – Shop Now at MZ-AT

Product Line

Products

Page
Page 1
Page 2
You're currently reading page 3

Show

ASTEC CHIRALDEX G-TA INTUVO 30M .25mm .&

SU-73033ASTINT

Product Type: GC Column Delivery Time: please inquire Chemistry: Chiral GC Column Type: Capillary Column Manufacturer: Merck Supelco Film Thickness [µm]: 0.12 µm Internal Diameter: 0.25 mm Length: 3 m

Astec® CHIRALDEX® G-DA Capillary GC Column, L x I.D. 30 m x 0.25 mm, df 0.12 µm

SU-72033AST

Page
Page 1
Page 2
You're currently reading page 3

Show

Technical Data

Astec Chiraldex^® A-TA:

High selectivity for oxygen containing analytes in the form of alcohols, ketones, acids, aldehydes and lactones
It is also highly selective for halogenated compounds.

Astec Chiraldex^® B-TA:

High selectivity for oxygen containing analytes in the form of alcohols, ketones, acids, aldehydes and lactones
It is also highly selective for halogenated compounds.

Astec Chiraldex^® G-TA:

Highest selectivity for oxygen-containing analytes like alcohols, diols and polyols, amino acids, hydroxy acids, amines as acyl derivatives, amino alcohols, halogens (Cl>Br>F), lactones, furans and pyrans.
This phase has been shown to be the most broadly-selective phase for the pharmaceutical industry, especially for the analysis of chiral intermediates and drug studies in various stages of clinical trials.

Astec Chiraldex^® G-PN:

High selectivity for lactones and aromatic amines. It is also suitable for epoxide separations.
Additionally, the analysis of styrene oxide can be accomplished on this phase (this analyte degrades on the TA phases).

Astec Chiraldex^® B-DP:

Good hydrolytic stability, broad chiral selectivity
Excellent for aliphatic and aromatic amines
Also good for many aliphatic and some aromatic esters

Astec Chiraldex^® G-DP:

Enhanced selectivity for both aliphatic and aromatic amines, in additional to aliphatic and some aromatic esters
Especially useful for polar racemates
Better hydrolytic and thermal stability than the Chiraldex^® G-TA

Astec Chiraldex^® G-BP:

High selectivity for amino acids, amines, and furans

Astec Chiraldex^® B-DM:

Useful for a number of free acids and bases
Able to perform most of the separations done on a beta permethylated phase, but with higher resolution
The selectivity of the B-DM covers applications of both the B-PM and B-PH phases, although with superior performance.

Astec Chiraldex^® G-DM:

Broad chiral selectivity, resolving aliphatic, olefenic, and aromatic enantiomers.
It combines the selectivities of the PM and PH phases

Astec Chiraldex^® B-PM:

General-purpose column used for the separation of acids, alcohols, barbitals, diols, epoxides, esters, hydrocarbons, ketones, lactones and terpenes.
Also, some underivatized alcohols and diols as well as some analytes with polar groups, i.e. tertiary amines, show excellent separation.

Astec Chiraldex^® A-DA:

Good for separations of heterocyclic amines
It has different selectivity from other phases and often shows reversal in elution from the PH phases

Astec Chiraldex^® B-DA:

Chiraldex^® B-DA requires that analytes possess a minimum of two ring structures, one of which is unsaturated (aromatic) α, β to the stereogenic center. Examples include fluoxetine, methylphenidate and chloropheniramine.
Effective for multi-ring analytes

Astec Chiraldex^® G-DA:

Good for separations of heterocyclic amines
It has different selectivity from other phases and often shows reversal in elution from the PH phases

Astec Chiraldex^® B-PH:

Show at least some selectivity to a great variety of analytes
Effective for saturated analytes with minimal functionality, saturated cyclics and bicyclics
This phase often shows a reversal of elution order (enantioreversal) compared to the B-DA phase

Column-Name	Chiral Selector	I.D.	Film thickness	Tmax
Chiraldex^® A-TA	2,6-Di-O-pentyl-3-trifluoroacetyl Derivat of α-Cyclodextrin	0.25 mm	0.12 µm	180 °C
Chiraldex^® B-TA	2,6-Di-O-pentyl-3-trifluoroacetyl Derivat of β-Cyclodextrin	0.25 mm	0.12 µm	180 °C
Chiraldex^® G-TA	2,6-Di-O-pentyl-3-trifluoroacetyl Derivat of γ-Cyclodextrin	0.25 mm	0.12 µm	180 °C
Chiraldex^® G-PN	2,6-Di-O-pentyl-3-propionyl Derivat of γ-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® B-DP	2,3-Di-O-propionyl-6-t-butyl silyl Derivat of β-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® G-DP	2,3-Di-O-propionyl-6-t-butyl silyl Derivat of γ-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® G-BP	2,6-Di-O-pentyl-3-butyryl Derivat of γ-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® B-DM	2,3-Di-O-methyl-6-t-butyl silyl Derivat of β-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® G-DM	2,3-Di-O-methyl-6-t-butyl silyl Derivat of γ-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® B-PM	2,3,6-Tri-O-methyl Derivat of β-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® A-DA	2,6-Di-O-pentyl-3-methoxy Derivat of α-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® B-DA	2,6-Di-O-pentyl-3-methoxy Derivat of β-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® G-DA	2,6-Di-O-pentyl-3-methoxy Derivat of γ-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C
Chiraldex^® B-PH	(S)-2-Hydroxy propyl methyl ether Derivat of β-Cyclodextrin	0.25 mm	0.12 µm	200‒220 °C

[1] Dependent on film thickness and whether you work at constant temperature or with a gradient.

Downloads

Applications

GC
Merck Supelco Applications-Notebook Vol2 GC, GC-MS, SPME, Air Monitoring

Contact Us

First Name*

Last Name*

Company*

Email*

Telephone

Message*

I have taken note of the Privacy Policy and agree that the data I have provided will be collected and stored electronically. My data will only be used strictly for the purpose of processing and responding to my request.

Fields marked with * must be filled in