Dr. Maisch / ReproSil Chiral

ReproSil Chiral

ReproSil Chiral HPLC column exist with different chiral selectors based on polysaccharides, Pirkle phases, proteins and cyclodextrins. There are also some phases available which are unique.

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MA-r112.nrr.0100
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Technical Data

Phase

Modification

Particle size / μm

USP Code

NR

Pirkle brush type

3, 5, 8, 12

N/A

NR-R

Pirkle brush type

8, 12

N/A

AM

Amylose tris-(3,5-dimethylphenyl) carbamate

3, 5, 10, 20

L51

AM-R

Amylose tris-(3,5-dimethylphenyl) carbamate

3, 5, 10

L51

OM

Cellulose tris-(3,5-dimethylphenyl) carbamate

3, 5, 10, 20

L40

OM-R

Cellulose tris-(3,5-dimethylphenyl) carbamate

3, 5, 10

L93

AMS

Amylose tris (S)-a-methylbenzyl carbamate

3, 5, 10

L90

AMS-R

Amylose tris (S)-a-methylbenzyl carbamate

3, 5

N/A

CM

Cellulose Tris-phenyl carbamate

3, 5, 10

L70

GM

Cellulose tris (4-methyl-phenyl) carbamate

5

N/A

JM

Cellulose tris (4-methylbenzoyl) carbamate

3, 5, 10

L80

JM-R

Cellulose tris (4-methylbenzoyl) carbamate

3, 5, 10

L107

BM

Cellulose (tris-benzoyl) carbamate

5

N/A

ZM

Cellulose tris-(3-chloro-4-methylphenyl)-carbamate

3, 5

N/A

XM

Cellulose tris-(4-chloro-3-methylphenyl)-carbamate

3, 5

N/A

ZA

Amylose tris-3-(chloro-4-methylphenyl) carbamate

3, 5

N/A

YM

Amylose tris-(5-chloro-2-methylphenyl)-carbamate

5

N/A

MIB

Cellulose tris-(3,5-dimethylphenyl)-carbamate

5

N/A

MIC

Cellulose tris-(3,5-dichlorophenyl) carbamate

3, 5

N/A

MIX

Cellulose tris-(4-chloro-3-methylphenyl)-carbamate

5, 10

N/A

MIZ

Cellulose tris-(3-chloro-4-methylphenyl) carbamate

3, 5, 10

N/A

MOF

Cellulose tris-(4-chlorophenyl) carbamate

5

N/A

MIA

Amylose tris-(3,5-dimethylphenyl) carbamate

5

N/A

MIF

Amylose tris-(3-chloro-4-methylphenyl) carbamate

5

N/A

MID

N/A

5

N/A

AGP

α1-acid glycoprotein

5

L41

HSA

human serum albumin

5

L79

PS

N/A

8

N/A

OH

N/A

8

N/A

AA

N/A

5, 8

L63

TAG

Teicoplanin Aglycon

5, 8, 10

L63

CA

N/A

5, 8

N/A

TG

N/A

5

N/A

Beta-CD-R(+) phenylethylamine

N/A

N/A

N/A

Chirobiotic-TAG

Teicoplanin Aglycon

10

L63

L-PhenylGlycine

N-(3,5-dinitrobenzoyl)-L-phenylglycine

5

L36

D-phenylglycine

N-(3,5-dinitrobenzoyl)-D-phenylglycine

3, 5

L36

L-leucine

N-(3,5-dinitrobenzoyl) L-leucine

5

N/A

L-proline

L-proline

5

N/A

L-hydroxy-proline

L-hydroxy-proline

5

L32

Beta-CD

Beta-cyclodextrin

5

L45

Beta-PM

Beta-cyclodextrin

5

L45

ReproSil Chiral-NR: Is suitable for the separation of aromatics, amides, carbamates, esters, alkylamines and compounds with multiple stereocentres in the normal phase.

 

ReproSil Chiral-AM: Is suitable for the separation of aromatics, amides, carbamates, esters, alkylamines and compounds with multiple stereocentres in the normal phase.

 

ReproSil Chiral-OM: Can be used if ReproSil Chiral-AM cannot completely separate the compounds; especially suitable for beta-blockers, compounds with similar functionalities and steroids.

 

ReproSil Chiral-AMS: If no separation can be achieved with ReproSil Chiral-AM, this phase should be used; especially suitable for β-lactams, glycidol derivates, epoxides, acids, natural products and heterocyclic compounds.

 

ReproSil Chiral-CM: Can be used if no separation can be achieved with ReproSil Chiral-Am or -OM.

 

ReproSil Chiral-GM: Special column for compounds which are only partially separated by ReproSil Chiral-OM and -CM.

 

ReproSil Chiral-JM: Especially suitable for the following compounds (or substances with similar structure): ibuprofen, ketamine, methadone, nicotine, steroids, acebutolol, albuterol, chlophedianol, mianserine and other compounds with a large substituent at the chiral centre.

 

ReproSil Chiral-BM: Is suitable for separations which are not sufficient with ReproSil Chiral-AMS or -JM.

 

ReproSil Chiral-AGP/-HSA: This phase is used in reversed phase; retention and enantioselectivity can be adjusted by pH, buffer concentration and an organic modifier.

 

ReproSil Chiral-PS: Is suitable for separation in normal- or reversed phase of aromatic compounds which contain sulfur or phosphorous.

 

ReproSil Chiral-OH: For aromatic alcohols with an OH group near the chiral centre.

 

ReproSil Chiral-AA: Special phase for amino acids (L-form elutes first).

 

ReproSil Chiral-TAG: Suitable for amino alcohols, N-blocked amino acids, α-hydroxy acids, oxazolidinones, hydantoins, imides and amino acids.

 

ReproSil Chiral-CA: Pirkle phase compatible with reversed phase for carboxyl groups near the chiral centre.

 

ReproSil Chiral-TG: Reversed phase with terguride for chiral FMOC- and dansyl amino acids.

 

ReproSil Chiral-L-PhenylGlycin: Brush-type phase for herbicides and pharmaceuticals.

 

ReproSil Chiral-L-Prolin: Davanako ligand exchange phase for amino acids, hydantiones, succinimides, gluthetimides, barbiturates and sulfoxides.

 

ReproSil L-Hydroxy-Prolin: Ligand exchange phase with copper sulfate.

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