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Anwender aus dem regulierten Umfeld (z. B. der Pharmaindustrie) sind vielfach an sogenannte Monographie-Methoden der europäischen- oder US-Pharmakopöe (Ph. Eur. bzw. USP) gebunden. Die in den Arzneibüchern festgelegten Spezifikationen für die Analytik der zu untersuchenden Stoffe müssen befolgt werden.
Das Europäische Arzneibuch (Ph. Eur.) enthält eine Reihe von allgemeinen Monographien zur Herstellung und Analytik von Arzneimitteln sowie einige allgemeine Anforderungen an die Darreichungsformen (Tabletten, Kapseln, Injektionen usw.).
In der untenstehenden Tabelle finden Sie für jede stationäre Phase die im Europäischen Arzneibuch (Ph. Eur.) beschrieben ist, die am besten geeigneten HPLC-Säulen, die über MZ-Analysentechnik GmbH erhältlich sind. Bitte kontaktieren Sie die MZ-Analysentechnik GmbH für Ihren Bedarf an HPLC-Säulen.
Description | Number | Recommended Column available from MZ-Analysentechnik GmbH |
Silica gel AD for chiral separation coated with Amylose tris (3,5-dimethylphenylcarbamate). | 1171700 | Daicel Chiralpak AD |
Silica gel for chiral separation, cellulose derivative coated with tris (3,5-dimethylphenylcarbamate). | 1110300 | Daicel Chiralcel OD |
Silica gel BC for chiral chromatography (Beta-Cyclodextrin). | 1161300 | Shinwa Ultron ES-CD Sumika Sumichiral OA-7000 Merck ChiraDex |
Silica gel CR+ for chiral chromatography (crown-ether). | 1192400 | Daicel Crownpak CR(+) |
Silica gel for chromatography. | 1076900 | PerfectSil 100 Sil |
Silica gel for chromatography, alkyl bonded for use with highly aqueous mobile phases. | 1160200 | MZ-Aqua Perfect C18 GL-Sciences InertSustainSwift C18 HALO AQ-C18 |
Silica gel for chromatography, alkyl bonded for use with highly aqueous mobile phases, endcapped. | 1176900 | MZ-Aqua Perfect C18 GL-Sciences InertSustainSwift C18 HALO AQ-C18 |
Silica gel for chromatography, alkylsilyl, solid core, endcapped. Spherical silica particles containing a non-porous solid silica core surrounded by a thinner outer porous silica coating with alkylsilyl groups. To minimize any interaction with basic compounds it is carefully endcapped to cover most of the remaining silanol groups. | 1194300 | HALO C18 HALO C8 Chromanik Sunshell C18 Chromanik Sunshell RP-Aqua |
Silica gel for chromatography, aminopropylmethylsilyl. | 1102400 | PerfectSil 120 NH2 PerfectChrom 100 NH2 |
Silica gel for chromatography, aminopropylsilyl. | 1077000 | PerfectSil 120 NH2 PerfectChrom 100 NH2 |
Silica gel for chromatography, Amylose derivative of. | 1109800 | Daicel Chiralpak IA Daicel Chiralpak ID Daicel Chiralpak IE Daicel Chiralpak IF Daicel Chiralpak IG Daicel Chiralpak IH |
Silica gel for chromatography, butylsilyl. Spheroidal 300 Å; pore volume: 0.6 cm3/g; area: 80 m2/g. | 1076200 | PerfectSil 300 C4 |
Silica gel for chromatography, butylsilyl, endcapped. | 1170500 | PerfectSil 120 C4 PerfectSil 300 C4 |
Silica gel for chromatography compatible with 100 % aqueous mobile phase, octadecylsilyl, endcapped. | 1188400 | MZ-Aqua Perfect C18 GL-Sciences InertSustainSwift C18 HALO AQ-C18 |
Silica gel for chromatography, crown-ether. | 1178000 | Daicel Crownpak CR(+) Daicel Crownpak CR-I(+) Daicel Crownpak CR(-) Daicel Crownpak CR-I(-) |
Silica gel for chromatography, cyanosilyl. | 1109900 | PerfectSil Target CN-3 PerfectSil 120 CN Orbit 100 CN |
Silica gel for chromatography, cyanopropylsilyl, endcapped, base-deactivated. | 1194200 | HALO ES-CN GL-Sciences InertSustain Cyano |
Silica gel for chromatography, cyanopropylsilyl, endcapped. | 1195000 | PerfectSil Target CN-3 HALO ES-CN GL-Sciences InertSustain Cyano |
Silica gel for chromatography, di-isobutyloctadecylsilyl. | 1140000 | HALO ES-C18 Zorbax StableBond C18 |
Silica gel for chromatography, diisopropylcyanopropylsilyl. | 1168100 | HALO ES-CN Zorbax StableBond CN |
Silica gel for chromatography, dimethyloctadecylsilyl. Irregular; area: 300 m2/g. | 1115100 | PerfectBond C18 |
Silica gel for chromatography, diol dihydroxypropyl, 100 Å pore size. | 1110000 | PerfectSil 100 Diol PerfectChrom 100 Diol |
Silica gel for chromatography, dodecylsilyl, endcapped. | 1179700 | SMT C12 |
Silica gel for chromatography, hexylsilyl. | 1077100 | PerfectChrom 100 C6 |
Silica gel for chromatography, hexylsilyl, endcapped. | 1174400 | SMT SAM-C6 |
Silica gel for chromatography, hydrophilic surface has been modified to provide hydrophilic characteristics. | 1077200 | HALO HILIC HALO Penta-HILIC |
Silica gel for chromatography, nitrile cyanopropylsilyl. | 1077300 | PerfectSil Target CN-3 PerfectSil 120 CN Orbit 100 CN |
Silica gel for chromatography, nitrile R1 chemically bonded nitrile groups. | 1077400 | PerfectSil Target CN-3 PerfectSil 120 CN Orbit 100 CN |
Silica gel for chromatography, nitrile R2 ultrapure silica (<20 ppm metal) with cyanopropylsilyl groups. | 1119500 | PerfectSil Target CN-3 PerfectSil 120 CN Orbit 100 CN |
Silica gel for chromatography, nitrile, endcapped with cyanopropylsilyl groups. | 1174500 | HALO ES-CN GL-Sciences InertSustain Cyano |
Silica gel for chromatography, octadecylsilyl. | 1077500 | PerfectSil Target ODS-3 HD PerfectSil Target ODS-3 PerfectSil ODS-3 PerfectSil 120 ODS-2 PerfectSil 300 C18 Orbit C18 MZ-Aqua Perfect C18 |
Silica gel for chromatography, octadecylsilyl R1 ultrapure silica (<20 ppm metals), pore size and C-load are indicated in the method. | 1110100 | PerfectSil Target ODS-3 HD PerfectSil Target ODS-3 PerfectSil ODS-3 PerfectSil 120 ODS-2 PerfectSil 300 C18 Orbit C18 MZ-Aqua Perfect C18 |
Silica gel for chromatography, octadecylsilyl R2 ultrapure silica; 150 Å pore size; 20% C-load; optimized for the analysis of PAHs. | 1115300 | MZ-PAH |
Silica gel for chromatography, octadecylsilyl, base-deactivated pretreated before the bonding by careful washing and hydrolyzing most of the superficial siloxane bridges to minimize the interaction with basic components. | 1077600 | PerfectSil Target ODS-3 HD PerfectSil Target ODS-3 PerfectBond BDS C18 |
Silica gel for chromatography, octadecylsilyl, endcapped. To minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1115400 | PerfectSil Target ODS-3 HD PerfectSil Target ODS-3 Chromanik Sunniest C18 |
Silica gel for chromatography, octadecylsilyl, endcapped R1 ultrapure silica (<20 ppm metal) 100 Å pore size; 19 % C-load. To minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1115401 | Orbit 100 C18 PerfectBond ODS-HD |
Silica gel for chromatography, octadecylsilyl, endcapped, base-deactivated; 100 Å pore size; 16 % C-load, pretreated before the bonding by careful washing and hydrolyzing most of the superficial siloxane bridges. To further minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1108600 | PerfectSil Target ODS-3 |
Silica gel for chromatography, octadecylsilyl, endcapped, base-deactivated R1; pretreated before the bonding by careful washing and hydrolyzing most of the superficial siloxane bridges To further minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1162600 | PerfectSil Target ODS-3 HD PerfectSil Target ODS-3 |
Silica gel for chromatography, octadecylsilyl, monolithic. | 1154500 | Merck Chromolith Performance RP-18e Merck Chromolith WP-300 RP-18 |
Silica gel for chromatography, octadecylsilyl, with polar embedded groups, endcapped; the particles are based on a mixture of silica chemically modified at the surface by the bonding of octadecylsilyl groups and silica chemically modified with a reagent providing a surface with chains having embedded polar groups. | 1177900 | MZ-Aqua Perfect C18 HALO AQ-C18 |
Silica gel for chromatography, octadecylsilyl, with polar incorporated groups, endcapped; the particles are based on silica, chemically modified with a reagent providing a surface with chains having polar incorporated groups and terminating octadecyl groups. | 1165100 | HALO RP-Amide Supelco Discovery RP-Amide C16 ACE C18-Amide |
Silica gel for chromatography, octadecylsilyl, ethylene-bridged (hybrid material). Synthetic, spherical ethylene-bridged hybrid particles, containing both organic (organosiloxanes) and inorganic (silica) components. | 1190500 | Waters Acquity BEH C18 Kromasil EternityXT C18 Chromanik SunArmor C18 Imtakt Dacapo DX C18 |
Silica gel for chromatography, octadecylsilyl, extra-dense bonded, endcapped. | 1188500 | PerfectSil Target ODS-3 HD Orbit 100 C18 InertSil ODS-HL SMT SAM-C18 [OD-Series] |
Silica gel for chromatography, octadecylsilyl, solid core, endcapped with spherical silica particles containing a non-porous solid silica core surrounded by a thin outer porous silica coating with octadecylsilyl groups. To minimize any interaction with basic compounds it is carefully endcapped to cover most of the remaining silanol groups. | 1193900 | HALO C18 Chromanik Sunshell C18 ACE UltraCore SuperC18 |
Silica gel for chromatography, octadecylsilyl, with extended pH range, endcapped (resistant to bases up to pH 11) | 1196700 | PerfectSil Target ODS-3 HD Kromasil EternityXT C18 Chromanik SunArmor C18 Imtakt Dacapo DX C18 |
Silica gel for chromatography, octylsilyl. | 1077700 | PerfectSil Target C8-3 HD PerfectSil Target C8-3 PerfectSil 100 C8-3 PerfectSil 120 C8 PerfectSil 300 C8 Orbit 100 C8 PerfectChrom 100 C8 |
Silica gel for chromatography, octylsilyl R1. Bonding of octylsilyl and methyl groups (double bonded phase). | 1077701 | PerfectSil Target C8-3 HD PerfectSil Target C8-3 PerfectSil 100 C8-3 PerfectSil 120 C8 PerfectSil 300 C8 Orbit 100 C8 |
Silica gel for chromatography, octylsilyl R3 ultrapure silica, bonding of octasilyl groups and sterically protected with branched hydrocarbons at the silanes. | 1155200 | Zorbax StableBond C8 |
Silica gel for chromatography, octylsilyl, base-deactivated pretreated before the bonding by careful washing and hydrolyzing most of the superficial siloxane bridges to minimize the interaction with basic components. | 1131600 | PerfectSil Target C8-3 HD PerfectSil Target C8-3 |
Silica gel for chromatography, octylsilyl, endcapped. To minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1119600 | PerfectSil Target C8-3 HD PerfectSil Target C8-3 |
Silica gel for chromatography, octylsilyl, endcapped, base-deactivated pretreated before the bonding by careful washing and hydrolyzing most of the superficial siloxane bridges to minimize the interaction with basic components. To further minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanols. | 1148800 | PerfectSil Target C8-3 HD PerfectSil Target C8-3 |
Silica gel for chromatography, octylsilyl, extra-dense bonded, endcapped. | 1200900 | PerfectSil Target C8-3 HD Orbit 100 C8 InertSustain C8 SMT SAM-C8 [O-Series] |
Silica gel for chromatography, phenylhexylsilyl. | 1153900 | GL Sciences InertSustain PhenylHexyl HALO Phenyl-Hexyl Kromasil EternityXT PhenylHexyl |
Silica gel for chromatography, phenylhexylsilyl, endcapped. To minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1170600 | GL Sciences InertSustain PhenylHexyl HALO Phenyl-Hexyl Kromasil EternityXT PhenylHexyl |
Silica gel for chromatography, phenylhexylsilyl, solid core, endcapped. Silica gel with spherical silica particles containing a non-porous solid silica core surrounded by a thin outer porous silica coating with phenylhexylsilyl groups. To minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1198900 | HALO Phenyl-Hexyl ACE UltraCore SuperPhenylHexyl |
Silica gel for chromatography, phenylsilyl. | 1110200 | PerfectSil 100 Phenyl-3 PerfectSil 120 Phenyl PerfectChrom 100 Phenyl |
Silica gel for chromatography, phenylsilyl, R1 spherical silica; pore size: 80 Å; surface area: 180 m2/g; C-load: 5.5%. | 1075700 | Zorbax StableBond Phenyl |
Silica gel for chromatography, phenylsilyl, endcapped. To minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1154900 | InertSustain Phenyl Waters XTerra Phenyl |
Silica gel for chromatogrpahy, phenylsilyl, endcapped, base-deactivated. | 1197900 | InertSustain Phenyl |
Silica gel for chromatography, (hybrid material), phenylsilyl, ethylene-bridged, endcapped. Synthetic, spherical ethylene-bridged hydrid particles containing both organic (organosiloxanes) and inorganic (silica) components, chemically modified at the surface by bonding of phenylsilyl groups. To minimize any interaction with basic compounds it’s carefully endcapped to cover most of the remaining silanol groups. | 1200700 | Waters XTerra Phenyl |
Silica gel for chromatography, propoxybenzene, endcapped. | 1174600 | ES Industries Sync Polar RP |
Silica gel for chromatography, propylsilyl. | 1170700 | Zorbax StableBond C3 SMT SAM-C3 ES Industries Chromegabond C3 |
Silica gel for chromatography, strong anion-exchange bonding of quaternary ammonium groups; pH limit of use: 2 to 8. | 1077800 | Partisphere SAX Hypersil Gold SAX ES Industries Chromegabond SAX Macherey-Nagel Nucleosil SB Sepax HP-SAX |
Silica gel for chromatography, strong cation-exchange bonding of sulfonic acid groups. | 1161400 | Partisphere SCX ES Industries Epic SCX Macherey-Nagel Nucleosil SA Sepax HP-SCX |
Silica gel for chromatography, trimethylsilyl. | 1115500 | PerfectBond C1 PerfectChrom 100 C1 |
Silica for size-exclusion chromatography. 10 μm silica with a very hydrophilic surface. Pore size average: 30 nm; pH stability 2 to 8; exclusion range for proteins: 1x103 to 3x105. | 1077900 | TSKgel G3000SW TSKgel G3000SWxl Shodex Protein KW-803 Sepax SRT-10 SEC-300 |
Silica gel OD for chiral separations. | 1110300 | Daicel Chiralcel OD |
Silica gel OJ for chiral separations coated with cellulose tris (4-methylbenzoate). | 1179800 | Daicel Chiralcel OJ |
Organosilica polymer, amorphous, octadecylsilyl. Synthetic, spherical hybrid particles containing both inorganic (silica) and organic (organosiloxanes) components, chemically modified at the surface by trifunctionally bonded octadecylsilyl groups. | 1144200 | XBridge BEH C18 |
Organosilica polymer, amorphous, octadecylsilyl, endcapped. Synthetic, spherical hybrid particles containing both inorganic (silica) and organic (organosiloxanes) components, chemically modified at the surface by trifunctionally bonded octadecylsilyl groups. To minimize any interaction with basic compounds, it is carefully endcapped to cover most of the remaining silanol groups. | 1178600 | XBridge BEH C18 |
Organosilica polymer for mass spectrometry, amorphous, octadecylsilyl, endcapped. Synthetic, spherical hybrid particles containing both inorganic (silica) and organic (organosiloxanes) components. To minimize any interaction with basic compounds, it is carefully endcapped to cover most of the remaining silanol groups. | 1164900 | XBridge BEH C18 |
Vinyl polymer for chromatography, amino alkyl. Spherical particles (5 μm) of a vinyl alcohol copolymer, bonding of amino alkyl groups. | 1191500 | Shodex Asahipak NH2P-50 |
Vinyl polymer for chromatography, octadecyl. Spherical particles (5 μm) of a vinyl alcohol copolymer, bonding of octadecyl groups on the hydroxyl groups. | 1155400 | Shodex Asahipak ODP-50 |
Vinyl polymer for chromatography, octadecylsilyl. Spherical particles (5 μm) of a vinyl alcohol copolymer bonded to an octadecylsilane. C-load: 17 %. | 1121600 | Shodex Asahipak ODP-50 |
Ion-exclusion resin for chromatography. A resin with sulfonic acid groups attached to a polymer lattice consisting of polystyrene crosslinked with divinylbenzene. | 1131000 | Concise Separations Coregel 87H3 Sepax Carbomix H |
Cation-exchange resin, strong. Strong cation-exchange resin in protonated form with sulfonic acid groups attached to a polymer lattice consisting of polystyrene cross-linked with divinylbenzene. | 1156800 | Concise Separations Coregel 87H3 Shodex SUGAR SH1011 Shodex SUGAR SH1821 Sepax Carbomix H |
Cation-exchange resin. A resin in protonated form with sulfonic acid groups attached to a polymer lattice consisting of polystyrene crosslinked with 8 % divinylbenzene. Available as spherical beads. | 1016700 | Concise Separations Coregel 87H3 Sepax Carbomix H |
Cation-exchange resin (Calcium form), strong. Resin in calcium form with sulfonic acid groups attached to a polymer lattice consisting of polystyrene cross-linked with 8 % divinylbenzene. | 1104600 | Concise Separations CarboSep CHO 87C Sepax Carbomix Ca |
Cation-exchange resin (Sodium form), strong. Resin in sodium form with sulfonic acid groups attached to a polymer lattice consisting of polystyrene cross-linked with divinylbenzene. | 1176100 | Concise Separations CarboSep CHO 87N Shodex SUGAR KS-801 to 806 Sepax Carbomix Na |